Photosensitive Reactions
Seeing Red Is Not A Good Thing
by Judie Bizzozero
After years of battling adult-onset tonsillitis I had my
tonsils removed at age 22. I had been on oral antibiotics two months prior to
surgery and IV antibiotics for a week afterward. My doctor, who used a laser to
remove my nearly golf-ball size tonsils that were obstructing my airway, told me
it was one of the worst cases he had seen in his practice. You might be
wondering what this has to do with the subject of photosensitivity and sunlight,
but I am getting to that. After I was given a clean bill of health I ventured to Mexico
for my family’s annual Labor Day trip. Unfortunately, my body was still harboring high levels of
antibiotics, and I suffered an intense photosentive reaction to the sun.
Every salon professional lives by the rule of sensible,
moderate and responsible tanning. That means educating your customers and staff
about the dangers of overexposure and the subject of photosensitivity. There are
instances where a customer may have a photosensitive reaction to ultraviolet
light and think it’s a sunburn, and it is up to the salon operator to educate
the consumer.
Defining Photosensitivity
Photosensitivity is a physical reaction that occurs in varying
degrees to a certain portion of the population. It occurs when different drugs or medical conditions react with ultraviolet light to cause the body to become more
sensitive regarding the skin’s acceptance of ultraviolet light.
The chemical may enter the skin several ways—orally,
topically or parenterally (not through the digestive tract)—but must be
present when the skin is exposed. Compounds that cause photosensitivity usually are cosmetic or
therapeutic in nature. Sometimes the chemical changes that occur reduce the skin’s
ability to defend or heal itself. Some medications specifically are designed to
enhance the immune system or reduce the immune response. There also are medical
conditions that cause a similar response.
Hopefully, a tanning customer will be aware of any medical
condition and will have been told by his or her physician to be careful of sun
exposure. However, it is the salon owner’s responsibility to inform the client
that ultraviolet light is the same whether it is emitted from the sun or from a
tanning unit.
There are a number of reactions that can occur from mixing
certain medications with ultraviolet light. The reaction is almost the opposite
of putting sunscreen lotion on the skin. For example, an SPF 8 lotion is
formulated to allow a person to remain in the sun for eight times as long
without burning. In the case of a photosensitizing agent, the individual only
may be able to be out in the sun for one-fourth the time he or she normally can
before getting erythema or sunburn.
It also is important to note that certain drugs are more
photosensitizing than others. For example, Tetracycline, Thiazide and
anti-cancer drugs such as Interferon top the list as most likely to cause a
severe reaction.
Salon operators must be aware that each individual is
different and there are varying portions of the population that will react to
any given medication or product.
Additional points to consider are formulation, metabolism,
elimination factors and photochemical reactivity, as well as the method of
administration. Factors associated with radiation include the special irradiance
of the ultraviolet source, dose and rate of delivery, number and frequency of
exposure, and the timing of the radiation relative to the presence of the
chemical in the body. Refer to a list of photosensitizing drugs and agents at
www.lookingfit.com. While this list is comprehensive, it does not list the newer
medications on the market. If you have any concerns, have your customers consult
with their doctors or pharmacists to see if they can withstand UV exposure—indoors
or outdoors.
Photoallergic Versus Phototoxic Reactions
There are two types of photosensitive reactions—phototoxic
and photoallergic. It can be difficult to distinguish between the two types of
reactions, and a substance or medication is capable of producing both reactions.
Photoallergic reactions usually
occur due to substances applied to the skin but can be caused by substances
ingested or injected. The reaction is the result of UV light structurally
changing the substance and, in turn, causing the skin to produce antibodies,
resulting in allergic reaction.
The symptoms typically appear as eczema-like skin conditions,
but also can present as lesions or hives. Symptoms usually appear on exposed
areas of the body, but the reaction can spread to nonexposed areas of the body.
Symptoms usually are delayed for 24 hours up to several days, and the recovery
period often is slower than that of phototoxic reactions.
It is important to note that photoallergic reactions are not
dependent on the amount of substance applied, ingested or injected. These
reactions require prior or prolonged exposure to the substance and do not occur
during the initial exposure to the substance. After the initial exposure period,
continued exposure to the substance, even in small amounts, will cause a
photoallergic reaction. They are more common in adults than children. Reactions can occur due to chemically related substances by
cross-sensitivity or cross-allergenicity.
Phototoxic reactions are more common
than photoallergic reactions and are caused by substances that either can be
ingested, applied to the skin or injected.
A phototoxic reaction occurs when the substance absorbs energy
from UV light and releases the energy into the skin. This energy causes skin
cell damage or death. The reaction usually occurs quickly—within seconds to hours
after exposure. The symptoms usually appear only on the parts of the body that
were exposed and present as a sunburn/erythema, pain, blistering,
hyperpigmentation and peeling.
Phototoxic reactions can occur on first exposure to a
substance and usually do not show cross-sensitivity.
What To Do
The clinical features of photosensitive reactions vary with
the chemical and the individual. Skin eruptions tend to occur in areas of
greatest exposure. In the event of an injury developing from overexposure to
ultraviolet light in a tanning facility, medical advice or attention should be
sought immediately. In the incidence of a photosensitive reaction, exposure to
ultraviolet radiation should be stopped at once.
Tanning facilities that are regulated by state law are
required to submit a written report of the incident within five working days.
For mild sunburn, cool compresses should be kept on the
affected area until the pain subsides. Soaking with Aveeno Oilated oatmeal, cold
cream and other bland medications are fine for mild sunburns. Do not use any
anesthetic ointment with the word “caine” in it, as this could cause a
severe allergic reaction. If an eye injury is incurred, immediately refer the
client to an emergency room or ophthalmologist.
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